Regulatory T-cell depletion in the setting of autologous stem cell transplantation for multiple myeloma: pilot study

BACKGROUND: Progression after high-dose melphalan with autologous stem cell transplantation (ASCT) in multiple myeloma (MM) may be due in part to immune dysfunction. Regulatory T (Treg) cells reconstitute rapidly after ASCT and inhibit immune responses against myeloma cells. METHODS: We performed a...

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Detalhes bibliográficos
Publicado no:J Immunother Cancer
Main Authors: Derman, Benjamin A, Zha, Yuanyuan, Zimmerman, Todd M, Malloy, Rebecca, Jakubowiak, Andrzej, Bishop, Michael R, Kline, Justin
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Publishing Group 2020
Assuntos:
Immune Cell Therapies and Immune Cell Engineering
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7057425/
https://ncbi.nlm.nih.gov/pubmed/31940591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jitc-2019-000286
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