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Human autoimmunity after lymphocyte depletion is caused by homeostatic T-cell proliferation
The association between lymphopenia and autoimmunity is recognized, but the underlying mechanisms are poorly understood and have not been studied systematically in humans. People with multiple sclerosis treated with the lymphocyte-depleting monoclonal antibody alemtuzumab offer a unique opportunity...
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| Main Authors: | , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3864306/ https://ncbi.nlm.nih.gov/pubmed/24282306 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1313654110 |
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