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The Development and Function of Regulatory B Cells Expressing IL-10 (B10 cells) Requires Antigen Receptor Diversity and TLR Signals()

Autoimmunity and inflammation are controlled in part by regulatory B cells, including a recently identified IL-10-competent CD1d(hi)CD5(+) B cell subset termed B10 cells that represents 1–3% of adult mouse spleen B cells. In this study, pathways that influence B10 cell generation and IL-10 productio...

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Detalhes bibliográficos
Main Authors: Yanaba, Koichi, Bouaziz, Jean-David, Matsushita, Takashi, Tsubata, Takeshi, Tedder, Thomas F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3733128/
https://ncbi.nlm.nih.gov/pubmed/19494269
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0900270
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