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Notch Inhibitors for Cancer Treatment

Notch signaling is an evolutionarily conserved cell signaling pathway involved in cell fate during development, stem cell renewal and differentiation in postnatal tissues. Roles for Notch in carcinogenesis, in the biology of cancer stem cells and tumor angiogenesis have been reported. These features...

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Detalhes bibliográficos
Main Authors: Espinoza, Ingrid, Miele, Lucio
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3732476/
https://ncbi.nlm.nih.gov/pubmed/23458608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pharmthera.2013.02.003
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