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Notch signaling: targeting cancer stem cells and epithelial-to-mesenchymal transition

Notch signaling is an evolutionarily conserved pathway involved in cell fate control during development, stem cell self-renewal, and postnatal tissue differentiation. Roles for Notch in carcinogenesis, the biology of cancer stem cells, tumor angiogenesis, and epithelial-to-mesenchymal transition (EM...

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Detalhes bibliográficos
Main Authors: Espinoza, Ingrid, Pochampally, Radhika, Xing, Fei, Watabe, Kounosuke, Miele, Lucio
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3772757/
https://ncbi.nlm.nih.gov/pubmed/24043949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S36162
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