Adenoviral Transduction of Human Acid Sphingomyelinase into Neo-Angiogenic Endothelium Radiosensitizes Tumor Cure

These studies define a new mechanism-based approach to radiosensitize tumor cure by single dose radiotherapy (SDRT). Published evidence indicates that SDRT induces acute microvascular endothelial apoptosis initiated via acid sphingomyelinase (ASMase) translocation to the external plasma membrane. En...

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Dades bibliogràfiques
Autors principals: Stancevic, Branka, Varda-Bloom, Nira, Cheng, Jin, Fuller, John D., Rotolo, Jimmy A., García-Barros, Mónica, Feldman, Regina, Rao, Shyam, Weichselbaum, Ralph R., Harats, Dror, Haimovitz-Friedman, Adriana, Fuks, Zvi, Sadelain, Michel, Kolesnick, Richard
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2013
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3732255/
https://ncbi.nlm.nih.gov/pubmed/23936314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0069025
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