A microRNA-30e/mitochondrial uncoupling protein 2 axis mediates TGF-β1-induced tubular epithelial cell extracellular matrix production and kidney fibrosis

Mitochondria dysfunction has been reported in various kidney diseases but how it leads to kidney fibrosis and how this is regulated is unknown. Here we found that mitochondrial uncoupling protein 2 (UCP2) was induced in kidney tubular epithelial cells after unilateral ureteral obstruction in mice an...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Jiang, Lei, Qiu, Wenjing, Zhou, Yang, Wen, Ping, Fang, Li, Cao, Hongdi, Zen, Ke, He, Weichun, Zhang, Chenyu, Dai, Chunsun, Yang, Junwei
التنسيق: Artigo
اللغة:Inglês
منشور في: Nature Publishing Group 2013
الموضوعات:
Basic Research
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC3731557/
https://ncbi.nlm.nih.gov/pubmed/23515048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ki.2013.80
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