Renal Fibrosis : Extracellular Matrix Microenvironment Regulates Migratory Behavior of Activated Tubular Epithelial Cells

During progression of chronic renal disease, qualitative and quantitative changes in the composition of tubular basement membranes (TBMs) and interstitial matrix occur. Transforming growth factor (TGF)-β(1)-mediated activation of tubular epithelial cells (TECs) is speculated to be a key contributor...

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Main Authors: Zeisberg, Michael, Maeshima, Yohei, Mosterman, Barbara, Kalluri, Raghu
Format: Artigo
Jezik:Inglês
Izdano: American Society for Investigative Pathology 2002
Teme:
Regular Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1850832/
https://ncbi.nlm.nih.gov/pubmed/12057905
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