Renal Fibrosis : Extracellular Matrix Microenvironment Regulates Migratory Behavior of Activated Tubular Epithelial Cells

During progression of chronic renal disease, qualitative and quantitative changes in the composition of tubular basement membranes (TBMs) and interstitial matrix occur. Transforming growth factor (TGF)-β(1)-mediated activation of tubular epithelial cells (TECs) is speculated to be a key contributor...

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Bibliographic Details
Main Authors: Zeisberg, Michael, Maeshima, Yohei, Mosterman, Barbara, Kalluri, Raghu
Format: Artigo
Language:Inglês
Published: American Society for Investigative Pathology 2002
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1850832/
https://ncbi.nlm.nih.gov/pubmed/12057905
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