A microRNA-30e/mitochondrial uncoupling protein 2 axis mediates TGF-β1-induced tubular epithelial cell extracellular matrix production and kidney fibrosis

Mitochondria dysfunction has been reported in various kidney diseases but how it leads to kidney fibrosis and how this is regulated is unknown. Here we found that mitochondrial uncoupling protein 2 (UCP2) was induced in kidney tubular epithelial cells after unilateral ureteral obstruction in mice an...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Jiang, Lei, Qiu, Wenjing, Zhou, Yang, Wen, Ping, Fang, Li, Cao, Hongdi, Zen, Ke, He, Weichun, Zhang, Chenyu, Dai, Chunsun, Yang, Junwei
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Nature Publishing Group 2013
Θέματα:
Basic Research
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3731557/
https://ncbi.nlm.nih.gov/pubmed/23515048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ki.2013.80
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