Post-Translational Control of IL-1β via the Human Papillomavirus Type 16 E6 Oncoprotein: A Novel Mechanism of Innate Immune Escape Mediated by the E3-Ubiquitin Ligase E6-AP and p53

Infections with high-risk human papillomaviruses (HPVs) are causally involved in the development of anogenital cancer. HPVs apparently evade the innate immune response of their host cells by dysregulating immunomodulatory factors such as cytokines and chemokines, thereby creating a microenvironment...

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Main Authors: Niebler, Martina, Qian, Xu, Höfler, Daniela, Kogosov, Vlada, Kaewprag, Jittranan, Kaufmann, Andreas M., Ly, Regina, Böhmer, Gerd, Zawatzky, Rainer, Rösl, Frank, Rincon-Orozco, Bladimiro
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2013
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3731255/
https://ncbi.nlm.nih.gov/pubmed/23935506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1003536
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