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HPV16 Oncoproteins Promote Cervical Cancer Invasiveness by Upregulating Specific Matrix Metalloproteinases

Production of matrix metalloproteinases (MMPs) for degradation of extracellular matrix is a vital step in cancer metastasis. We investigated the effects of HPV16 oncoproteins (16E6, 16E6*I and 16E7), either individually or combined, on the transcription of 7 MMPs implicated in cervical cancer invasi...

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Detalhes bibliográficos
Main Authors: Kaewprag, Jittranan, Umnajvijit, Wareerat, Ngamkham, Jarunya, Ponglikitmongkol, Mathurose
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3742460/
https://ncbi.nlm.nih.gov/pubmed/23967226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0071611
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