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Synthetic glycopeptides reveal the glycan specificity of HIV-neutralizing antibodies

A new class of glycan-reactive HIV-neutralizing antibodies, including PG9 and PG16, has been recently discovered that appear to recognize novel glycopeptide epitopes on HIV-1 gp120. However, further characterization and reconstitution of the precise neutralizing epitopes are complicated by the heter...

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Autors principals: Amin, Mohammed N., McLellan, Jason S., Huang, Wei, Orwenyo, Jared, Burton, Dennis R., Koff, Wayne C., Kwong, Peter D., Wang, Lai-Xi
Format: Artigo
Idioma:Inglês
Publicat: 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3730851/
https://ncbi.nlm.nih.gov/pubmed/23831758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.1288
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