Llwytho...

K(+) efflux is the Common Trigger of NLRP3 inflammasome Activation by Bacterial Toxins and Particulate Matter

The NLRP3 inflammasome is an important component of the innate immune system. However, its mechanism of activation remains largely unknown. We show that NLRP3 activators including bacterial pore-forming toxins, nigericin, ATP and particulate matter caused mitochondrial perturbation or the opening of...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Muñoz-Planillo, Raúl, Kuffa, Peter, Martínez-Colón, Giovanny, Smith, Brenna L., Rajendiran, Thekkelnaycke M., Núñez, Gabriel
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2013
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3730833/
https://ncbi.nlm.nih.gov/pubmed/23809161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2013.05.016
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