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Sensing and Reacting to Microbes via the Inflammasomes
Inflammasomes are multi-protein complexes that activate Caspase-1 which subsequently leads to the maturation of the proinflammatory cytokines IL-1β and IL-18 as well as pyroptosis, a form of cell death induced by bacterial pathogens. Members of the Nod-like receptor family including NLRP1, Nlrp3 and...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2012
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3449002/ https://ncbi.nlm.nih.gov/pubmed/22430785 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.2231 |
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