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The Inflammasome: A Caspase-1 Activation Platform Regulating Immune Responses and Disease Pathogenesis

The inflammasome is a multi-protein complex that mediates activation of caspase-1 which promotes the secretion of the proinflammatory cytokines IL-1β and IL-18 as well as pyroptosis, a form of cell death induced by bacterial pathogens. Members of the Nod-like receptor family including NLRP1, NLRP3 a...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Franchi, Luigi, Eigenbrod, Tatjana, Muñoz-Planillo, Raúl, Nuñez, Gabriel
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2009
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2820724/
https://ncbi.nlm.nih.gov/pubmed/19221555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.1703
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