Mitochondrial DNA damage induces apoptosis in senescent cells

Senescence is a cellular response to damage and stress. The senescence response prevents cancer by suppressing the proliferation of cells with a compromised genome and contributes to optimal wound healing in normal tissues. Persistent senescent cells are also thought to drive aging and age-associate...

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Detalhes bibliográficos
Main Authors: Laberge, R-M, Adler, D, DeMaria, M, Mechtouf, N, Teachenor, R, Cardin, G B, Desprez, P-Y, Campisi, J, Rodier, F
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3730395/
https://ncbi.nlm.nih.gov/pubmed/23868060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2013.199
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