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New Insights into the Nature of Autoinflammatory Diseases from Mice with Nlrp3 Mutations

Mutations in the NLRP3 (CIAS1, Cryopyrin) gene are associated with cryopyrin-associated periodic syndromes (CAPS), auto inflammatory diseases characterized by excessive interleukin-1 (IL-1) production and neutrophilia in blood and tissues. Recent studies with gene-targeted mice expressing mutations...

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Kaydedildi:
Detaylı Bibliyografya
Asıl Yazarlar: Meng, Guangxun, Strober, Warren
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2010
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3729261/
https://ncbi.nlm.nih.gov/pubmed/20201022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.200940191
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