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New Insights into the Nature of Autoinflammatory Diseases from Mice with Nlrp3 Mutations
Mutations in the NLRP3 (CIAS1, Cryopyrin) gene are associated with cryopyrin-associated periodic syndromes (CAPS), auto inflammatory diseases characterized by excessive interleukin-1 (IL-1) production and neutrophilia in blood and tissues. Recent studies with gene-targeted mice expressing mutations...
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2010
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3729261/ https://ncbi.nlm.nih.gov/pubmed/20201022 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.200940191 |
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