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Allosteric Inhibitors of the NS3 Protease from the Hepatitis C Virus

The nonstructural protein 3 (NS3) from the hepatitis C virus processes the non-structural region of the viral precursor polyprotein in infected hepatic cells. The NS3 protease activity has been considered a target for drug development since its identification two decades ago. Although specific inhib...

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Detalhes bibliográficos
Main Authors: Abian, Olga, Vega, Sonia, Sancho, Javier, Velazquez-Campoy, Adrian
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3728351/
https://ncbi.nlm.nih.gov/pubmed/23936097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0069773
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