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Conformational Stability of Hepatitis C Virus NS3 Protease

The hepatitis C virus NS3 protease is responsible for the processing of the nonstructural region of viral precursor polyprotein in infected hepatic cells. NS3 has been considered a target for drug discovery for a long time. NS3 is a zinc-dependent serine protease. However, the zinc ion is not involv...

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Detalhes bibliográficos
Main Authors: Abian, Olga, Vega, Sonia, Neira, Jose Luis, Velazquez-Campoy, Adrian
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2998608/
https://ncbi.nlm.nih.gov/pubmed/21112306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2010.10.037
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