Chimeric Sindbis viruses dependent on the NS3 protease of hepatitis C virus.
The hepatitis C virus (HCV) NS3 protease cleaves the viral polyprotein at specific sites to release the putative components of the HCV replication machinery. Selective inhibition of this enzyme is predicted to block virus replication, and NS3 is thus considered an attractive candidate for developmen...
Guardat en:
| Publicat a: | J Virol |
|---|---|
| Autors principals: | , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Microbiology (ASM)
1997
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC191198/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8995667/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.71.2.1417-1427.1997 |
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