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Chimeric Sindbis viruses dependent on the NS3 protease of hepatitis C virus.

The hepatitis C virus (HCV) NS3 protease cleaves the viral polyprotein at specific sites to release the putative components of the HCV replication machinery. Selective inhibition of this enzyme is predicted to block virus replication, and NS3 is thus considered an attractive candidate for developmen...

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Detalles Bibliográficos
Publicado en:J Virol
Principais autores: Filocamo, G, Pacini, L, Migliaccio, G
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology (ASM) 1997
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC191198/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8995667/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.71.2.1417-1427.1997
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