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NS3 Protease from Hepatitis C Virus: Biophysical Studies on an Intrinsically Disordered Protein Domain

The nonstructural protein 3 (NS3) from the hepatitis C virus (HCV) is responsible for processing the non-structural region of the viral precursor polyprotein in infected hepatic cells. NS3 protease activity, located at the N-terminal domain, is a zinc-dependent serine protease. A zinc ion, required...

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Detalhes bibliográficos
Main Authors: Vega, Sonia, Neira, Jose L., Marcuello, Carlos, Lostao, Anabel, Abian, Olga, Velazquez-Campoy, Adrian
Formato: Artigo
Idioma:Inglês
Publicado em: Molecular Diversity Preservation International (MDPI) 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3742187/
https://ncbi.nlm.nih.gov/pubmed/23803659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms140713282
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