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RNA Binding by the NS3 Protease of the Hepatitis C Virus

The hepatitis C virus (HCV) nonstructural protein 3 (NS3) is essential for the processing of the HCV polyprotein, the replication of HCV RNA, and to short circuit innate immunity signaling. NS3 contains an N-terminal domain with protease activity and a C-terminal domain with helicase activity. The t...

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Bibliographic Details
Main Authors: Vaughan, Robert, Li, Yi, Fan, Baochang, Ranjith-Kumar, C. T., Kao, C. Cheng
Format: Artigo
Language:Inglês
Published: 2012
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3467334/
https://ncbi.nlm.nih.gov/pubmed/22814430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virusres.2012.07.007
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