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Identification and functional characterization of the nascent RNA contacting residues of the hepatitis C virus RNA-dependent RNA polymerase

Understanding how the hepatitis C virus (HCV) RNA-dependent RNA polymerase (RdRp) interacts with nascent RNA would provide valuable insight into the virus's mechanism for RNA synthesis. Using a peptide mass fingerprinting method and affinity capture of peptides reversibly cross-linked to an alk...

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Bibliographic Details
Main Authors: Vaughan, Robert, Fan, Baochang, You, Jin-Sam, Kao, C. Cheng
Format: Artigo
Language:Inglês
Published: Cold Spring Harbor Laboratory Press 2012
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3404374/
https://ncbi.nlm.nih.gov/pubmed/22736798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.031914.111
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