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Augmenting Autophagy to Treat Acute Kidney Injury during Endotoxemia in Mice
OBJECTIVE: To determine that 1) an age-dependent loss of inducible autophagy underlies the failure to recover from AKI in older, adult animals during endotoxemia, and 2) pharmacologic induction of autophagy, even after established endotoxemia, is of therapeutic utility in facilitating renal recovery...
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| Autori principali: | , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Public Library of Science
2013
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3728340/ https://ncbi.nlm.nih.gov/pubmed/23936035 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0069520 |
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