CaMKIV-dependent preservation of mTOR expression is required for autophagy during LPS-induced inflammation and acute kidney injury()

Autophagy, an evolutionarily conserved homeostasis process regulating biomass quantity and quality, plays a critical role in the host response to sepsis. Recent studies show its calcium dependence, but the calcium sensitive regulatory cascades have not been defined. Here we describe a novel mechanis...

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Hlavní autoři: Zhang, Xianghong, Howell, Gina M., Guo, Lanping, Collage, Richard D., Loughran, Patricia A., Zuckerbraun, Brian S., Rosengart, Matthew R.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4215705/
https://ncbi.nlm.nih.gov/pubmed/25070845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1302798
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