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Muscle Ring Finger 1 (MuRF1) and MuRF2 are Necessary but Functionally Redundant During Developmental Cardiac Growth and Regulate E2F1-Mediated Gene Expression In Vivo

AIMS: Muscle ring finger (MuRF) proteins have been implicated in the transmission of mechanical forces to nuclear cell signaling pathways through their association with the sarcomere. We recently reported that MuRF1, but not MurF2, regulates pathologic cardiac hypertrophy in vivo. This was surprisin...

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Autori principali: Willis, Monte S., Wadosky, Kristine M., Rodríguez, Jessica E., Schisler, Jonathan C., Lockyer, Pamela, Hilliard, Eleanor G., Glass, David J., Patterson, Cam
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3728166/
https://ncbi.nlm.nih.gov/pubmed/23512667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbf.2969
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