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Muscle Ring Finger 1 (MuRF1) and MuRF2 are Necessary but Functionally Redundant During Developmental Cardiac Growth and Regulate E2F1-Mediated Gene Expression In Vivo

AIMS: Muscle ring finger (MuRF) proteins have been implicated in the transmission of mechanical forces to nuclear cell signaling pathways through their association with the sarcomere. We recently reported that MuRF1, but not MurF2, regulates pathologic cardiac hypertrophy in vivo. This was surprisin...

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Bibliografiske detaljer
Main Authors: Willis, Monte S., Wadosky, Kristine M., Rodríguez, Jessica E., Schisler, Jonathan C., Lockyer, Pamela, Hilliard, Eleanor G., Glass, David J., Patterson, Cam
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3728166/
https://ncbi.nlm.nih.gov/pubmed/23512667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbf.2969
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