Rare Variants in Genes Encoding MuRF1 and MuRF2 Are Modifiers of Hypertrophic Cardiomyopathy

Modifier genes contribute to the diverse clinical manifestations of hypertrophic cardiomyopathy (HCM), but are still largely unknown. Muscle ring finger (MuRF) proteins are a class of muscle-specific ubiquitin E3-ligases that appear to modulate cardiac mass and function by regulating the ubiquitin-p...

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Bibliographische Detailangaben
Hauptverfasser: Su, Ming, Wang, Jizheng, Kang, Lianming, Wang, Yilu, Zou, Yubao, Feng, Xinxing, Wang, Dong, Ahmad, Ferhaan, Zhou, Xianliang, Hui, Rutai, Song, Lei
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2014
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4100095/
https://ncbi.nlm.nih.gov/pubmed/24865491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms15069302
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