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Toll-Like Receptor–2/6 and Toll-Like Receptor–9 Agonists Suppress Viral Replication but Not Airway Hyperreactivity in Guinea Pigs

Respiratory virus infections cause airway hyperreactivity (AHR). Preventative strategies for virus-induced AHR remain limited. Toll-like receptors (TLRs) have been suggested as a therapeutic target because of their central role in triggering antiviral immune responses. Previous studies showed that c...

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Detalhes bibliográficos
Main Authors: Drake, Matthew G., Evans, Scott E., Dickey, Burton F., Fryer, Allison D., Jacoby, David B.
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3727870/
https://ncbi.nlm.nih.gov/pubmed/23449736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2012-0498OC
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