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Toll-like receptor 7 agonists are potent and rapid bronchodilators in guinea pigs

BACKGROUND: Respiratory tract viral infections result in asthma exacerbations. Toll-like receptor (TLR) 7 is a receptor for viral single-stranded RNA and is expressed at high levels in the lungs. OBJECTIVE: Because TLR7 polymorphisms are associated with asthma, we examined the effects of TLR7 agonis...

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Detalhes bibliográficos
Main Authors: Kaufman, Elad H., Fryer, Allison D., Jacoby, David B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3066064/
https://ncbi.nlm.nih.gov/pubmed/21167577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2010.10.029
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