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Toll-like Receptor 7 Rapidly Relaxes Human Airways

Rationale: Toll-like receptors (TLRs) 7 and 8 detect respiratory virus single-stranded RNA and trigger an innate immune response. We recently described rapid TLR7-mediated bronchodilation in guinea pigs. Objectives: To characterize TLR7 expression and TLR7-induced airway relaxation in humans and in...

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Hlavní autoři: Drake, Matthew G., Scott, Gregory D., Proskocil, Becky J., Fryer, Allison D., Jacoby, David B., Kaufman, Elad H.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Thoracic Society 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3826186/
https://ncbi.nlm.nih.gov/pubmed/23924358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.201303-0442OC
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