Mast Cell-restricted, Tetramer-forming Tryptases Induce Aggrecanolysis in Articular Cartilage by Activating Matrix Metalloproteinase-3 and -13 Zymogens()

Mouse mast cell protease (mMCP)-6-null C57BL/6 mice lost less aggrecan proteoglycan from the extracellular matrix of their articular cartilage during inflammatory arthritis than wild-type (WT) C57BL/6 mice, suggesting that this mast cell (MC)-specific mouse tryptase plays prominent roles in articula...

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Main Authors: Magarinos, Natalia J., Bryant, Katherine J., Fosang, Amanda J., Adachi, Roberto, Stevens, Richard L., McNeil, H. Patrick
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2013
Ábhair:
Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3727140/
https://ncbi.nlm.nih.gov/pubmed/23797671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1300856
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