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Mast cells contribute to autoimmune inflammatory arthritis via their tryptase•heparin complexes

Although mast cells (MCs) often are abundant in the synovial tissues of patients with rheumatoid arthritis (RA), MC’s contribution to joint inflammation and cartilage loss remains poorly understood. MC-restricted tryptase•heparin complexes have pro-inflammatory activity, and significant amounts of h...

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Detalhes bibliográficos
Main Authors: Shin, Kichul, Nigrovic, Peter A., Crish, James, Boilard, Eric, McNeil, H. Patrick, Larabee, Katherine S., Adachi, Roberto, Gurish, Michael F., Gobezie, Reuben, Stevens, Richard L., Lee, David M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2610352/
https://ncbi.nlm.nih.gov/pubmed/19109198
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