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Impaired contractile function due to decreased cardiac myosin binding protein C content in the sarcomere
Mutations in cardiac myosin binding protein C (MyBP-C) are a common cause of familial hypertrophic cardiomyopathy (FHC). The majority of MyBP-C mutations are expected to reduce MyBP-C expression; however, the consequences of MyBP-C deficiency on the regulation of myofilament function, Ca(2+) homeost...
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| Main Authors: | , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Physiological Society
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3727108/ https://ncbi.nlm.nih.gov/pubmed/23666674 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00929.2012 |
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