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Coumestrol from the national cancer Institute’s natural product library is a novel inhibitor of protein kinase CK2

BACKGROUND: Casein kinase 2 (CK2) is involved in various cellular events such as proliferation, apoptosis, and the cell cycle. CK2 overexpression is associated with multiple human cancers and may therefore be a promising target for cancer therapy. To identity novel classes of inhibitors for CK2, we...

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Main Authors: Liu, Shu, Hsieh, David, Yang, Yi-Lin, Xu, Zhidong, Peto, Csaba, Jablons, David M, You, Liang
格式: Artigo
語言:Inglês
出版: BioMed Central 2013
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3726451/
https://ncbi.nlm.nih.gov/pubmed/23845105
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2050-6511-14-36
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