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Coumestrol from the national cancer Institute’s natural product library is a novel inhibitor of protein kinase CK2
BACKGROUND: Casein kinase 2 (CK2) is involved in various cellular events such as proliferation, apoptosis, and the cell cycle. CK2 overexpression is associated with multiple human cancers and may therefore be a promising target for cancer therapy. To identity novel classes of inhibitors for CK2, we...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
BioMed Central
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3726451/ https://ncbi.nlm.nih.gov/pubmed/23845105 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2050-6511-14-36 |
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