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Identification of hematein as a novel inhibitor of protein kinase CK2 from a natural product library
BACKGROUND: Casein kinase 2 (CK2) is dysregulated in various human cancers and is a promising target for cancer therapy. To date, there is no small molecular CK2 inhibitor in clinical trial yet. With the aim to identify novel CK2 inhibitors, we screened a natural product library. METHODS: We adopted...
Gorde:
| Egile Nagusiak: | , , , , , , , |
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| Formatua: | Artigo |
| Hizkuntza: | Inglês |
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BioMed Central
2009
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2696466/ https://ncbi.nlm.nih.gov/pubmed/19419583 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-9-135 |
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