Coumestrol Epigenetically Suppresses Cancer Cell Proliferation: Coumestrol Is a Natural Haspin Kinase Inhibitor

Targeting epigenetic changes in gene expression in cancer cells may offer new strategies for the development of selective cancer therapies. In the present study, we investigated coumestrol, a natural compound exhibiting broad anti-cancer effects against skin melanoma, lung cancer and colon cancer ce...

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Detalhes bibliográficos
Main Authors: Jong-Eun Kim, Sung-Young Lee, Mi Jang, Hyo-Kyung Choi, Jong Hun Kim, Hanyong Chen, Tae-Gyu Lim, Zigang Dong, Ki Won Lee
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2017-10-01
Colecção:International Journal of Molecular Sciences
Assuntos:
cancer
coumestrol
haspin kinase
histone H3
Acesso em linha:https://www.mdpi.com/1422-0067/18/10/2228
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