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Genetic and Epigenetic Alterations of the NF2 Gene in Sporadic Vestibular Schwannomas

BACKGROUND: Mutations in the neurofibromatosis type 2 (NF2) tumor-suppressor gene have been identified in not only NF2-related tumors but also sporadic vestibular schwannomas (VS). This study investigated the genetic and epigenetic alterations in tumors and blood from 30 Korean patients with sporadi...

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Détails bibliographiques
Auteurs principaux: Lee, Jong Dae, Kwon, Tae Jun, Kim, Un-Kyung, Lee, Won-Sang
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3266248/
https://ncbi.nlm.nih.gov/pubmed/22295085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0030418
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