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Colon cancer progression is driven by APEX1-mediated upregulation of Jagged

Aberrant expression of apurinic-apyrimidinic endonuclease–1 (APEX1) has been reported in numerous human solid tumors and is positively correlated with cancer progression; however, the role of APEX1 in tumor progression is poorly defined. Here, we show that APEX1 contributes to aggressive colon cance...

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Detalhes bibliográficos
Main Authors: Kim, Mi-Hwa, Kim, Hong-Beum, Yoon, Sang Pil, Lim, Sung-Chul, Cha, Man Jin, Jeon, Young Jin, Park, Sang Gon, Chang, In-Youb, You, Ho Jin
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3726152/
https://ncbi.nlm.nih.gov/pubmed/23863623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI65521
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