Ape1/Ref-1 Induces Glial Cell-Derived Neurotropic Factor (GDNF) Responsiveness by Upregulating GDNF Receptor α1 Expression

Apurinic/apyrimidinic endonuclease 1 (Ape1/Ref-1) dysregulation has been identified in several human tumors and in patients with a variety of neurodegenerative diseases. However, the function of Ape1/Ref-1 is unclear. We show here that Ape1/Ref-1 increases the expression of glial cell-derived neurot...

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Autori principali: Kim, Mi-Hwa, Kim, Hong-Beum, Acharya, Samudra, Sohn, Hong-Moon, Jun, Jae Yeoul, Chang, In-Youb, You, Ho Jin
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2663317/
https://ncbi.nlm.nih.gov/pubmed/19188437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01484-08
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