Osteoclast precursors in murine bone marrow express CD27 and are impeded in osteoclast development by CD70 on activated immune cells

Osteoclasts (OCs) are bone-resorbing cells that are formed from hematopoietic precursors. OCs ordinarily maintain bone homeostasis, but they can also cause major pathology in autoimmune and inflammatory diseases. Under homeostatic conditions, receptor activator of nuclear factor kappa-B (RANK) ligan...

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Main Authors: Xiao, Yanling, Song, Ji-Ying, de Vries, Teun J., Fatmawati, Christien, Parreira, Diana B., Langenbach, Geerling E. J., Bąbała, Nikolina, Nolte, Martijn A., Everts, Vincent, Borst, Jannie
格式: Artigo
語言:Inglês
出版: National Academy of Sciences 2013
主題:
Biological Sciences
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3725107/
https://ncbi.nlm.nih.gov/pubmed/23832783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1216082110
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