Osteoclast precursors in murine bone marrow express CD27 and are impeded in osteoclast development by CD70 on activated immune cells

Osteoclasts (OCs) are bone-resorbing cells that are formed from hematopoietic precursors. OCs ordinarily maintain bone homeostasis, but they can also cause major pathology in autoimmune and inflammatory diseases. Under homeostatic conditions, receptor activator of nuclear factor kappa-B (RANK) ligan...

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Hlavní autoři: Xiao, Yanling, Song, Ji-Ying, de Vries, Teun J., Fatmawati, Christien, Parreira, Diana B., Langenbach, Geerling E. J., Bąbała, Nikolina, Nolte, Martijn A., Everts, Vincent, Borst, Jannie
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2013
Témata:
Biological Sciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3725107/
https://ncbi.nlm.nih.gov/pubmed/23832783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1216082110
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