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Osteoclast precursors in murine bone marrow express CD27 and are impeded in osteoclast development by CD70 on activated immune cells

Osteoclasts (OCs) are bone-resorbing cells that are formed from hematopoietic precursors. OCs ordinarily maintain bone homeostasis, but they can also cause major pathology in autoimmune and inflammatory diseases. Under homeostatic conditions, receptor activator of nuclear factor kappa-B (RANK) ligan...

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Detalhes bibliográficos
Main Authors: Xiao, Yanling, Song, Ji-Ying, de Vries, Teun J., Fatmawati, Christien, Parreira, Diana B., Langenbach, Geerling E. J., Bąbała, Nikolina, Nolte, Martijn A., Everts, Vincent, Borst, Jannie
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3725107/
https://ncbi.nlm.nih.gov/pubmed/23832783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1216082110
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