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Fat cells directly sense temperature to activate thermogenesis

Classic brown fat and inducible beige fat both dissipate chemical energy in the form of heat through the actions of mitochondrial uncoupling protein 1. This nonshivering thermogenesis is crucial for mammals as a defense against cold and obesity/diabetes. Cold is known to act indirectly through the s...

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Hlavní autoři: Ye, Li, Wu, Jun, Cohen, Paul, Kazak, Lawrence, Khandekar, Melin J., Jedrychowski, Mark P., Zeng, Xing, Gygi, Steven P., Spiegelman, Bruce M.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3725077/
https://ncbi.nlm.nih.gov/pubmed/23818608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1310261110
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