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Translation Initiation Requires Cell Division Cycle 123 (Cdc123) to Facilitate Biogenesis of the Eukaryotic Initiation Factor 2 (eIF2)

The eukaryotic translation initiation factor 2 (eIF2) is central to the onset of protein synthesis and its modulation in response to physiological demands. eIF2, a heterotrimeric G-protein, is activated by guanine nucleotide exchange to deliver the initiator methionyl-tRNA to the ribosome. Here we r...

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Bibliografiske detaljer
Main Authors: Perzlmaier, Angelika F., Richter, Frank, Seufert, Wolfgang
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3724614/
https://ncbi.nlm.nih.gov/pubmed/23775072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.472290
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