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Identification of Residues That Underpin Interactions within the Eukaryotic Initiation Factor (eIF2) 2B Complex
Eukaryotic initiation factor 2B (eIF2B) plays a key role in protein synthesis and in its control. It comprises five different subunits, α-ϵ, of which eIF2Bϵ contains the catalytic domain. Formation of the complete complex is crucial for full activity and proper control of eIF2B. Mutations in the gen...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Biochemistry and Molecular Biology
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3318736/ https://ncbi.nlm.nih.gov/pubmed/22238342 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.331553 |
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