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Dynamics of protofibril elongation and association involved in Aβ42 peptide aggregation in Alzheimer’s disease

BACKGROUND: The aggregates of a protein called, ‘Aβ’ found in brains of Alzheimer’s patients are strongly believed to be the cause for neuronal death and cognitive decline. Among the different forms of Aβ aggregates, smaller aggregates called ‘soluble oligomers’ are increasingly believed to be the p...

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Detalhes bibliográficos
Main Authors: Ghosh, Preetam, Kumar, Amit, Datta, Bhaswati, Rangachari, Vijayaraghavan
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3724481/
https://ncbi.nlm.nih.gov/pubmed/20946608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-11-S6-S24
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